Spermatozoa produced in the testes are initially incapable of fertilising an oocyte. To acquire this capacity, they undergo capacitation within the female reproductive tract, a complex process ...

Fertilization is the union of two cells: an egg and a sperm. Before the egg and the sperm fuse, an event known as the "acrosome reaction" needs to occur in the sperm. Now, a team from Osaka University ...

Ferlins are a family of single transmembrane proteins with multiple calcium ion (Ca2+) binding C2 domains involved in Ca2+-mediated membrane fusion. Among other processes, ferlins participate in the ...

Osaka, Japan – Fertilization is the union of two cells: an egg and a sperm. Before the egg and the sperm fuse, an event known as the “acrosome reaction” needs to occur in the sperm. Now, a team from ...

Sperm chemotaxis and the acrosome reaction constitute two critical processes that ensure fertilisation across a broad range of species. Chemotaxis refers to the guided movement of spermatozoa along ...