McCaffrey has a long injury history. If he's picked up a new knock, it's something that fans will naturally be concerned about. But if the 49ers knew to pretty much immediately leak Schefter the status report, it's a bit odd that McCaffrey had to go on the report at all.

The Titans have announced that Moore is inactive, thrusting reserves like tackle Oli Udoh.

McCaffrey has 849 rushing yards and 806 receiving yards with four games left in the regular season as he approaches the 1,000-1,000 mark for the second time in his career.