Drug absorption, distribution, metabolism and elimination (ADME)-related genes are genes related to the absorption, distribution, metabolism and elimination of drugs. They can be classified into four ...
ADME is the abbreviation for absorption, distribution, metabolism and excretion. ADME studies are designed to investigate how a chemical (e.g., a drug compound) is processed by a living organism.
Historically, it was not possible to detect ADME problems until the IND application preparation stage, which often led to “serious disruption of the development process, and often resulted in closure ...
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