Blocking antibodies have transformed oncology over the past quarter century. But agonist antibodies that boost downstream signalling have proved much harder to develop, despite great promise. In ...

Dr. Paul Christo answers the question: 'What Is An Agonist-Antagonist Medicine?' — -- Question: What Is An Agonist-Antagonist Medicine And When Is It Used For Pain Relief? Answer: ...

Partial opioid agonists have mixed or limited action when they bind to your opioid receptors. So, doctors often use them to treat opioid use disorder. Protein receptor sites are like keyholes on the ...

Brendon Yee, PhD, professor and respiratory and sleep physician, Woolcock Institute of Medical Research, discusses the success of ALKS 2680, an investigational oral selective orexin 2 receptor agonist ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. The first generic GLP-1 receptor agonist in the U.S. has ...

We conducted a phase 2, randomized, placebo-controlled trial of TAK-994, an oral orexin receptor 2–selective agonist, in patients with narcolepsy type 1. Patients with confirmed narcolepsy type 1 ...

Please provide your email address to receive an email when new articles are posted on . It is currently recommended to withhold glucagon-like peptide-1 receptor agonists before surgery. This ...

Rachael Link is a registered dietitian and health writer based in San Francisco. She completed her undergraduate degree at the University of Central Missouri and holds a master’s degree from New York ...

Anti-obesity drugs such as semaglutide (Ozempic, Wegovy) are also promising for the treatment of alcohol use disorder and alcohol-associated liver disease, as growing evidence suggests they reduce the ...

(RTTNews) - Takeda Pharmaceutical Company Limited (TAK) said that a safety signal has emerged in Phase 2 studies of TAK-994, an investigational oral orexin agonist. As an immediate precautionary ...