A pore smaller than one nanometer reads peptide sequences amino acid by amino acid, pinpointing single-site Alzheimer's mutations and modifications with single-residue resolution.

While DNA sequencing is a useful tool for determining what's going on in a cell or a person's body, it only tells part of the story. Protein sequencing could soon give researchers a wider window into ...

Using nanopore DNA sequencing technology, researchers from TU Delft and the University of Illinois have managed to scan a single protein. By slowly moving a linearized protein through a tiny nanopore, ...

While researchers have already succeeded in obtaining sequence information from single DNA strands, a further major challenge in bioanalytics is the direct determination of the amino acid sequence ...

Structural disorder is vital for proteins' function in diverse biological processes. It is therefore highly desirable to be able to predict the degree of order and disorder from amino acid sequence.

Proteins are the workhorses of cells and provide vital insights to cell health and disease function. Immunoassays and mass spectrometry are well established methods for studying proteins and have led ...

Amino acid sequencing has become a highly automated and efficient process. It plays an invaluable role in protein biochemistry, and is making an increasing contribution to modern molecular biology and ...

DNA and RNA sequencing has become the new watchword for the biological researchers, as this tells them exactly what is going on at cellular level in health and disease. However, it is a partial ...

Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...

Antibodies are the immune system's precision tools for recognizing and neutralizing viruses, bacteria and other foreign substances that can make us ill. These proteins circulate in the bloodstream and ...