After screening a library of over 100,000 small molecules, researchers from the Broad Institute of MIT and Harvard have identified compounds that act on a novel target in the malaria parasite, ...

The battle to control malaria infection has been hampered by many factors, including emerging drug resistance. Now, two papers published in Nature have opened up the door to a wealth of compounds that ...

Among patients with incident rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) who were new antimalarial users, adherence to antimalarials (≥ 90% of doses) was associated with a lower ...

Artemisinin-based combination treatments (ACTs) are seen as an important tool in the global effort to roll back malaria. With parasite resistance to chloroquine increasing rapidly in many parts of the ...

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance. The ...

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Observational study results suggest antimalarials may have a broad protective effect against systemic damage in lupus nephritis. Among patients with biopsy-confirmed lupus nephritis, antimalarial ...