Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably ...

A new study has uncovered a key mechanism that helps one of the deadliest brain cancers evade the immune system, according to ...

A research team led by Prof. Liu Qingsong at the Institute of Health and Medical Technology, the Hefei Institutes of Physical ...

Precancers, defined as normal-appearing or morphologically altered tissues with a risk of oncogenesis, exhibit various detectable manifestations across anatomical sites, including epithelial dysplasia ...

A study recently published in Current Molecular Pharmacology has uncovered a novel mechanism by which the long non‑coding RNA ...

Cancer cells rewire their metabolic circuits to support rapid proliferation, survival under stress and metastatic spread. Central to this rewiring are kinase signalling pathways that sense nutrient ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

A new study identifies sex-specific glioblastoma immune mechanism where GABA reprograms granulocytic MDSCs to fuel tumor growth solely in females.

A massive 10-year population study reveals that neovascular age-related macular degeneration (nAMD) is linked to an increased ...