"If it ain't broke, don't fix it," goes the old adage, which Rice University professor James Chappell completely ignored in a ...

Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides, which happens constantly. Without this process, we would die.

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more ...

Allison McClure, Ph.D., is an assistant professor in the Department of Biochemistry and Molecular Genetics at the CU School of Medicine. She is focused on learning all about how cells replicate, or ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

A study headed by researchers at NYU Langone Health has found that herpes simplex virus 1 (HSV-1) partially liquifies the tightly packed, gel-like interior of human cell nuclei to help copy itself ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

For almost 60 years, scientists have tried to understand why DNA doesn’t replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...