Cytokines are essential mediators of immune functions and regulate many other biological processes, ranging from fetal development to ageing. Dysregulation of cytokine responses can substantially ...

Cytokines are soluble mediators that orchestrate cell-to-cell communication in both immune surveillance and pathological processes. In cancer, aberrant cytokine networks foster tumour initiation, ...

The right signals can make or break an organoid model. From growth and differentiation to downstream drug testing, cytokines and growth factors are critical to creating cultures researchers can rely ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases in mouse ...

Macrophages remain ready to fight infection thanks to signaling molecules left behind by previous infections. That is according to new research from scientists at the University of California, Los ...

A pharmacovigilance analysis of nearly five million adverse-event reports finds that liver injury after CAR T-cell therapy is ...

A new single‑cell sequencing method is giving researchers a clearer view of how immune cells actually behave—capturing not just what they plan to do, but what they are doing in real time. The platform ...

A new study links baseline IFN-γ-based NK cell activity to ex vivo expansion capacity of autologous NK cells, offering a ...

Autoimmune diseases result from a complex interaction of immune system imbalances, marked by a breakdown in self-tolerance and sustained inflammation. At the core of this dysregulation are ...

Scientists at Nagoya University in Japan studied what happens when macrophages—a type of immune cell—encounter dying cancer cells in tumors and discovered a mechanism that accelerates tumor growth.

People often get immunotherapy as a treatment for cancer. These immunotherapy treatments can be effective, but they may cause your immune system to have an unnatural response. Your body, as a result ...