DNA gyrase, the sole type II topoisomerase in Mycobacterium tuberculosis, is indispensable for maintaining DNA supercoiling during replication and transcription. Historically, fluoroquinolones have ...
Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...
New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our understanding of how bacteria manage DNA. The methods have enabled researchers to ...
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...
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