Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

There are only about 20,000 different genes in the human genome, yet our bodies are filled with an incredible diversity of cell types performing innumerable functions. The key to that diversity in ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone ...