The thermodynamics of DNA secondary structure formation is fundamental to understanding diverse biological processes, such as DNA replication 1 and repair 2. It also underlies many biotechnological ...
To understand how oncogenes affect genome organization, it is essential to visualize fundamental processes such as DNA replication and transcription at high resolution in intact cells. At the same ...
If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...
Most people are familiar with the DNA double-helix. Its twisted ladder shape forms because the long pieces of DNA that make up our genome are exactly complementary—every adenine paired to a thymine, ...
To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...
Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...
In a recent study published in PNAS, researchers introduced the Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects by self-supervised pretraining on ...
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