Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Current drug discovery workflows rely on the synthesis and bioactivity assessment of large compound libraries, both processes which heavily depend on high-throughput (HT) experimentation to be able to ...

Our laboratory’s expertise is in the development and application of direct mass spectrometry technologies for tissue analysis and disease detection. Our research projects are focused on the ...

This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

MIT engineers have demonstrated the first fully 3D-printed, droplet-emitting electrospray engine. The device, which would be ideal for enabling small satellites to make in-orbit maneuvers, can be ...

Researchers demonstrated the first fully 3D-printed, droplet-emitting electrospray engine. The low-cost device can be fabricated more quickly than traditional thrusters, potentially from on board a ...

Master the principles of MS/MS in proteomics to improve peptide sequencing accuracy. This guide covers fragmentation methods, ...

In mass spectrometry, a sample is analyzed to determine its molecular composition through the generation of a spectrum that reveals the masses of its component parts. A transfer line introduces the ...

Mass spectrometry is a powerful analytical method used to identify and characterize molecules. People often mistakenly think that the data outputted by the technique come in the form of a mass ...