As interest in therapeutic TIDES grows, regulatory agencies are increasingly requiring more rigorous characterization to ensure patient safety, drug efficacy, and quality. To meet these demands, ...

This article describes a completely automated, benchtop NMR-based approach for directly quantifying nonionic surfactants (NISs) such as polysorbates and poloxamer 188 in biologic drug formulations. By ...

Fragment-based drug discovery (FBDD) has emerged as a transformative approach in medicinal chemistry by focusing on the identification of small chemical fragments that bind to biologically relevant ...

NMR (Nuclear Magnetic Resonance) spectroscopy is a powerful analytical technique that provides detailed information about the structure, dynamics, and chemical environment of molecules at the atomic ...

Since its development in the first half of the 20th century, Nuclear magnetic resonance (NMR) spectroscopy is an integral tool across various scientific disciplines. The method’s relevance and power ...

RNA plays a crucial role in every phase of the cell life cycle, with misregulation frequently resulting in disease. Recent breakthroughs in understanding RNA biochemistry, structure, and dynamics have ...