Panelists discuss how immunoglobulin A (IgA) nephropathy develops through a complex 4-hit cascade involving aberrant IgA1 glycosylation, anti-glycan antibody formation, immune complex deposition, and ...

It has only recently become known that two parallel systems of blood formation exist in the body, originating from different precursor cells. Researchers at the German Cancer Research Center (DKFZ) ...

Panelists discuss how current immunoglobulin A (IgA) nephropathy treatments primarily target downstream inflammatory pathways of the 4-hit cascade, with emerging therapies now beginning to address ...

Immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) is a rare disease that affects the filtering units in your kidneys (glomeruli). There are many types of glomerular diseases.

IgA nephropathy, also known as Berger’s disease, is a progressive, autoimmune, chronic kidney disease that predominantly affects adults between the ages of 20 and 40. It is characterized by the ...

Kidney Disease: Improving Global Outcomes (KDIGO) has issued comprehensive, evidence-based recommendations for clinicians managing immunoglobulin A nephropathy (IgAN) and immunoglobulin A vasculitis ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ ...

The newborn's immune system is a highly specialized mechanism that takes months to mature and become capable of effectively responding to pathogens. During this phase, adequate nutritional support, ...