In 2006 immunologist and 2025 Nobel prize winner Shimon Sakaguchi co-wrote an article in Scientific American that now feels ...

Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

Fred Ramsdell, a Bainbridge resident for three decades, was part of a three-person team honored earlier in October.

The discovery of regulatory T cells links genetic, cellular, and clinical research, bridging basic science and therapeutic ...

Once cells’ quality control mechanism is activated, IRGQ (red) accumulates in special cell organelles, the lsysosomes (green). This is also where the degradation of the non-functional MHC-I molecules ...

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi won this year’s Physiology or Medicine Nobel Prize for their discoveries ...

As our hair goes gray and our muscles weaken with age, our immune system also changes. In particular, the stem cells that ...

Our immune system works to fight infections immediately, but also maintain long-term immunity. Two waves of protection help neutralize and eliminate disease, including the innate and adaptive immune ...

Nobel laureate Shimon Sakaguchi reflects on the role of regulatory T cells in peripheral immune tolerance and how the cells ...

A new study published in the journal eNeuro provides evidence that cannabidiol (CBD), a nonpsychoactive compound derived from cannabis, may help reduce brain inflammation associated with Alzheimer’s ...