Different interferons can be obtained from the same animal species depending on the cells and (or) the inducers used. Interferons of type I and type II differ not only antigenically but also in ...

New research shows how pseudorabies virus protein VP22 hijacks DDX21 to inhibit cGAS activation, weakening type I interferon ...

In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...

This is a preview. Log in through your library . Abstract The microbiota is known to modulate the host response to influenza infection through as-yet-unclear mechanisms. We hypothesized that ...

In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help ...

Objective Patients with systemic lupus erythematosus (SLE) commonly develop lupus nephritis (LN), the most frequent severe ...

Researchers examined data from controlled trials and found that taking vitamin D2 led to a reduction in vitamin D3 levels, in ...

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus ...