It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones.

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

Bones consist of an extracellular organic matrix housed in inorganic mineral crystals. The organic matrix is mainly comprised of collagen type 1 amongst other proteins. Bones contain marrow and ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

What keeps bones able to remodel themselves and stay healthy? A team has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load. The ...

The From Labs to Lives Blog connects everyday topics with UC Davis research. Each post is reviewed by our experts, ensuring you always get useful information you can trust. Because we can’t see them, ...