Session 1: Making Grignard reagents and safety aspects of making and handling Grignard reagents. This presentation will cover the main ways for preparing organomagnesium compounds, and consider their ...

A time-honored laboratory exercise for students of organic chemistry is to make a Grignard reagent from magnesium metal turnings and an organohalide so that they can then use the resulting nucleophile ...

α-Chiral amines are of significant importance in medicinal chemistry, asymmetric synthesis and material science, but methods for their efficient synthesis are scarce. In particular, the synthesis of α ...

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The reaction utilizes an iron catalyst together with an N-heterocyclic carbene (NHC) ligand, which suppresses unwanted side reactions to promote highly selective nucleophile addition. In organic ...