Microtubules are dynamic, tubular polymers composed of αβ-tubulin dimers that form an essential framework within eukaryotic cells. They orchestrate a wide range of cellular functions including ...

The motion of motor proteins on biopolymers is important for diverse biological processes. Actin, microtubules, and nucleic acids can serve as one-dimensional tracks on which motor proteins move.

Sub-membrane microtubule array, known to prevent excessive glucose-stimulated insulin secretion, depends on kinesin-1 KIF5B, which moves microtubules to both generate and remodel this array, ...

An image of a large segment of a microtubule with a peeling tip. The colors highlight the different protofilaments that make up the tubule. The protofilaments are long biopolymers consisting of the ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside ...

KIF18A is a kinesin motor protein that moves toward the plus-end of spindle microtubules during mitosis. Inhibition of KIF18A disrupts spindle microtubule dynamics and chromosome alignment, ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...