The artist’s impression shows how the HIV capsid penetrates the jelly-like permeability barrier of a nuclear pore. To smuggle its genome through this defense line into the cell nucleus, it has evolved ...

In order for HIV to replicate, the viral genome must enter into the cell nucleus and integrate into the host cell chromosome. Previous work suggests that the entry proceeds through nuclear pore ...

A long-standing mystery in bile acid biology has been solved. Bile acids are often introduced as digestion helpers, but they are also powerful chemical messengers that help coordinate metabolism ...

Scientists from Duke-NUS Medical School (Duke-NUS) have derived a structural model of a transporter at the blood-brain barrier called Mfsd2a. This is the first molecular model of this critical ...

Vitamin B 1, also known as thiamine, is essential for the survival of our cells. The human body can't produce it, but we can maintain healthy levels of this vitamin by eating foods like salmon, ...

Using cryo-EM structure determination, molecular dynamics simulations, and electrophysiological analyses, researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences ...

BioIVT, a leading provider of research models and services for drug development, today announced that it has acquired Santa Clara, CA-based Optivia Biotechnology and its comprehensive portfolio of ...