Both the ghrelin and motilin receptor have been investigated as therapeutic targets for digestive disorders, but no compounds with selective activity are yet in clinical use Ligand-dependent ...
Background: Motilin, a peptide hormone has a direct excitatory effect on circular smooth muscle strips derived from the human colon. Reduced plasma motilin concentration has been reported in adults ...
LONDON (MarketWatch) -- Kosan Biosciences, Inc. announced a license agreement with pharmaceutical giant Pfizer, Inc. for its motilin agonist program. The agreement includes Kosan's clinical candidate ...
As Kosan Biosciences Inc. focuses on its cancer therapeutics, it licensed out its motilin agonist program to Pfizer Inc. in a worldwide deal worth up to $250 million in up-front and milestone payments ...
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