Multiple organ failure following severe trauma arises from a complex interplay of systemic inflammation, immune dysregulation, microvascular dysfunction and metabolic derangements. Initial tissue ...

Pediatric sepsis is a serious issue globally and is a significant cause of illness and death among infants and children. Refractory septic shock and multiple organ dysfunction syndrome are the primary ...

Innate and adaptive immune cells coordinate the excessive inflammatory response known as a cytokine storm in acute respiratory distress syndrome, leading to alveolar–capillary barrier damage, ...

The Journal of the American Medical Association (JAMA) has recently published the updated version of the Sequential Organ Failure Assessment (SOFA), the global reference system in intensive care ...

Researchers from 28 countries have proposed updating the Sequential Organ Failure Assessment (SOFA) score to better measure organ dysfunction in critically ill patients admitted to the ICUs. SOFA 2, ...

A 19-month-old child faced a life-threatening ordeal after accidentally ingesting mosquito-repellent liquid, leading to severe lung damage and multiple organ complications. After nearly three weeks of ...

A National Institutes of Health (NIH)-supported clinical trial has found that intravenous acetaminophen reduced sepsis patients' risk of having organ injury or developing acute respiratory distress ...

It's been over a month since five women died in Rajasthan's Kota after undergoing surgical challenges during pregnancy. What killed these five women and what triggered recent cases of acute kidney ...