Struggling with alcohol cravings? Naltrexone targets the brain's reward center to minimize drinking urges and reduce harmful ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Few patients with opioid toxicity receive opioid agonist therapy (OAT), data suggest. In a retrospective study that examined about 21,000 hospital visits related to opioid use disorder (OUD) in ...

Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive. Because the molecules suppress breathing and heart function, those drugs can ...

In the week following any hospital visit for an overdose, only 1 in 18 people with opioid use disorder begin a treatment known to be highly effective in reducing illness and deaths, according to new ...

Addressing overdoses from “street drugs” containing potent synthetic opioids poses a key challenge when utilizing opioid antagonists. A standard approach to known or suspected opioid overdose includes ...

For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...

Fentanyl does not need much room to kill. A dose the size of a few grains of salt can slow breathing until it stops. The drug ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.