We're 10 weeks into the NFL season, and we already have a relatively clear picture of which teams will be playing the postseason, with a few potential exception

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2025 NFL Week 11 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine. New users can get $50 in Pick6 credits at DraftKings when they play $5.

Florio’s pick: Patriots 30, Jets 20. Simms’s pick: Patriots 27, Jets 10. The Commanders are sinking. The Dolphins have a little bit more to play for. Florio’s pick: Colts 23, Falcons 17. Simms’s pick: Colts 24, Falcons 20. Panthers at Falcons (-3.5) Carolina blew a chance to get to 6-4. The Falcons have been way too inconsistent.

As always, our two survivor columnists, Renee Miller and Adam Gretz, are here to answer your specific survivor strategy questions and share their picks for Week 11. Keep an eye out for our calls for questions in future weeks, and Adam and Renee will try to answer as many questions as we can fit in. Good luck!

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 11 on a 47-32 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.