A method for rapidly screening biotoxins produced by algae could help speed up the discovery of useful compounds. Single-celled algae with a pair of hair-like appendages, dinoflagellates produce large ...

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Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and ...

Researchers produce a precursor to tetrahydrocannabinol (THC) in amoebae with hopes to produce high yields of pure medicinal THC using biotechnology. A group at the Leibniz Institute for Natural ...

Researchers from the UCLA Henry Samueli School of Engineering and Applied Science have taken a major step forward in the field of metabolic engineering, successfully using the bacterium Escherichia ...

Researchers published a study confirming the discovery of a new process for producing active complex compounds in amoebae. In particular, studying the process of olivetolic acid production (a compound ...

Enzymes are substances that cause chemical reactions. Certain types of enzymes, such as polyketide synthases and nonribosomal peptide synthetases, have the ability to shuffle their parts, allowing ...

Polyketides are a large class of secondary metabolites that have become indispensible in the modern medicine. They are made by massive enzymes called polyketide synthases, which contain multiple ...

Video shows the mechanism of action of a polyketide synthase module reported by a University of Michigan research team. A new study solves long-standing mysteries about how bacterial ...

As the effectiveness of antibiotics meant to fight the deadly superbug Clostridioides difficile, or C. diff, wanes, a research team at the University of Houston is seeing positive results of a new ...