New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...

A new study suggests the immune system relies on repeated rounds of mutation and competition rather than perfect selection to ...

Targeted mutagenesis systems are critical for protein evolution. Current deaminase-T7 RNA polymerase fusion systems enable gene-specific mutagenesis but remain limited to certain model organisms. Here ...

Most cancers originate from genetic abnormalities, specifically the accumulation of somatic mutations. These mutations accumulate in normal cells in all organs of healthy individuals and are driven by ...

Using next generation gene sequencing techniques, cancer researchers at UT Southwestern Medical Center have identified more than 3,000 new mutations involved in certain kidney cancers, findings that ...