Six years after the COVID-19 pandemic, which had claimed over 7 million lives worldwide by April 2024 (figures are no longer being tracked), we are still debating the origins of this novel virus. The ...

A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting ...

Researchers have identified a dual therapeutic strategy that combined inhibition of a key SARS-CoV-2 viral enzyme with suppression of a host inflammatory pathway, with preclinical evidence that ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...

Researchers from the Institute for Basic Science of Korea and collaborating institutions have designed a new class of peptide-based inhibitors targeting a crucial interface within the SARS-CoV-2 ...

Since the start of the COVID-19 pandemic, there has been controversy surrounding the origins of SARS-CoV-2. New research from the University of California, San Diego (UCSD), School of Medicine ...

The question of the origin of SARS-CoV-2 continues to occupy scientists, the media, and the public intensely even 5 years after the onset of the COVID-19 pandemic. Where the virus came from, when and ...

A multi-institutional study led by researchers at the University of Alabama at Birmingham and the University of North Carolina at Chapel Hill has revealed a previously underappreciated mechanism by ...

In a recent review published in the journal Cell Communication and Signaling, a team of researchers in Egypt and the United States explored the direct and indirect mechanisms of T lymphocyte-linked ...

During the first few years of the COVID-19 pandemic, the virus SARS-CoV-2 was detected in an increasing number of non-human animal species. This included many wild animal species as well as domestic ...