Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...
Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary Gergely, Eileen O’Toole, Ammon Crapo, Loren Hough, J. Richard McIntosh ...
The alternative text for this image may have been generated using AI. Figure 4: Non-phosphorylatable MKLP1 induces lagging chromosomes, and non-phosphorylatable ZEN-4 localizes in embryos depleted of ...
Eukaryotes assemble a microtubule-based spindle apparatus that separates chromosomes into daughter cells during cell division. Although studies of how spindle microtubules capture kinetochores of ...
Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...
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