Our DNA is organized into chromosomes, and the ends of chromosomes are protected with caps called telomeres; when cells divide, they lose a very small amount of DNA from those ends. Short telomeres ...

Cancer is a significant cause of death worldwide and many efforts have been devoted to the development of methods for early detection. Telomerase are considered as a tumor biomarker for early ...

Gene therapy with telomerase was developed by CNIO in 2012 and has proved effective in mice against infarction, as well as in mouse models of aplastic anaemia and idiopathic pulmonary fibrosis ...

Telomerase, because of its role in cancer and aging, has long been a target of drug companies who want to block it to stop the uncontrolled cell growth characteristic of cancer, or boost it to create ...

Researchers at the University of Maryland (UMD) and the National Institutes of Health (NIH) have identified a previously unknown role for the enzyme telomerase. Until now, the only known role for ...

Research has recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA. Research from the ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...