Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative ...
Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.
Eukaryotic translation initiation factors in trypanosomatids display a fascinating divergence from those in higher eukaryotes. Foundational research has revealed that these parasites possess multiple ...
The translation initiation factor eIF4E-binding protein-mediated regulation of protein translation by interfering with assembly of mRNA cap-binding complex eIF4F is well described in mammalian and ...
The repair of photosystem II (PSII) is particularly sensitive to oxidative stress and the inhibition of repair is associated with oxidative damage to the translational elongation system in the ...
The Merrick laboratory seeks to identify all of the eukaryotic translation initiation factors and determine their sequential utilization in the initiation pathway. A secondary goal is to characterize ...
The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer. Research published in the open access journal BMC Cancer shows that eEF1A2, which is usually present ...
The Lloyd Lab main research focus is the enterovirus infection triggers of integrated stress responses and Type 1 Diabetes. Enteroviruses such as poliovirus and coxsackievirus shut off cap-dependent ...
Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have ...
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