Antivirulence drugs are a new type of therapeutic drug that target virulence factors, potentially revitalising the drug-development pipeline with new targets. As antivirulence drugs disarm the ...

A University of Alberta research team has identified a new drug target to treat harmful E. coli bacteria—which cause nearly 250,000 deaths a year from urinary tract infections (UTI) and are becoming ...

Figure 1: The type III secretion system of Gram-negative bacterial pathogens injects virulence factors into host cells. The second class of TTSS-associated chaperones, which are the subject of this ...

Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for organisms ranging from single-celled bacteria to human beings. Some ...

The visualization revealed that virulence activation is achieved through the interaction of ToxR or TcpP with the ...

Please provide your email address to receive an email when new articles are posted on . Infection is a challenging and dreaded complication of any surgical procedure, particularly so in orthopedic ...

The emergence of new variants of concern (VOC) has slowed down progress against the COVID-19 pandemic in 3 ways: 1. by increasing the transmissibility of the virus and hence the reproduction number; 2 ...

Vol. 184, No. S1, Disease Ecology and EvolutionA Symposium Organized by Curtis M. Lively (August 2014), pp. S47-S57 (11 pages) AbstractHost immunity plays an important role in the evolution of ...

Background: Between February and June 2021, the initial wild-type strains of SARS-CoV-2 were supplanted in Ontario, Canada, by new variants of concern (VOCs), first those with the N501Y mutation (i.e.