The Buffalo Bills will play the New England Patriots in the NFL's Week 5 Sunday Night Football game. Kickoff is scheduled for 8:20 p.m. ET on Sunday, Oct. 5, 2025, at Highmark Stadium in Orchard Park, N.Y. The game will be broadcast on NBC and available to ...

The New England Patriots, behind young quarterback Drake Maye, handed the Buffalo Bills their first loss of the season on 'Sunday Night Football.'

Buffalo and New England meet on Sunday Night Football in Week 5 for the next episode in this long-standing AFC East rivalry. The Bills have dominated this matchup over the Patriots since 2020, sporting an 8-3 record against New England that includes a ...

Is Buffalo's loss to the Patriots a 'wake up call' for Josh Allen and Bills? Yahoo Sports Daily hosts Caroline Fenton and Jason Fitz react to the Buffalo Bills’ Sunday night loss to the New England Patriots and discuss what it means for their Super Bowl hopes. Watch the full episode of Yahoo Sports Daily on YouTube or YahooSports.TV. Now Playing

The latest iteration of AFC armageddon takes place Sunday afternoon at Highmark Stadium when the 5-2 Bills host the 5-3 Chiefs in a game that, as always, figures to have huge ramifications down the line when it comes to deciding division races and conference playoff seeding.