Treatment of rheumatoid arthritis (RA) has improved substantially during the last decades, mainly due to the development and introduction in everyday practice of new, highly efficacious, ...

The International Myositis Classification Criteria Project consortium, the Euromyositis register and the Juvenile Dermatomyositis Cohort Biomarker Study and Repository (JDRG) (UK and Ireland).

Methods Anti-Ku-positive patients were retrieved through four immunology departments. Clusters were derived from unsupervised multiple correspondence analysis, not including the disease’s diagnosis, ...

Objective This study explored the dynamic functional connective (DFC) alterations in patients with rheumatoid arthritis (RA) and investigated the correlation between the neuropsychiatric symptoms, ...

RMD Open publishes high quality peer-reviewed original research covering the full spectrum of musculoskeletal disorders, rheumatism and connective tissue diseases, including osteoporosis, spine and ...

Objective Cellular ageing of the immune system has been suggested to play a role in the pathogenesis of rheumatoid arthritis ...

Background Immune checkpoint inhibitors (ICIs) have significantly improved outcomes for patients with cancer. However, these therapies are associated with adverse events including de novo ...

Objectives To explore the toxicity of low-dose methotrexate (MTX), an uncommon, but life-threatening event. Methods We analysed the presentation, course and risk factors of all patients admitted to ...

Objective Successful uptake of biosimilars in rheumatology is limited by lack of real-world evidence regarding effectiveness of biosimilar-to-biosimilar switching. We investigated infliximab ...

Objectives To identify factors associated with the effectiveness and safety of Janus kinase (JAK) inhibitors in patients with rheumatoid arthritis (RA), as reflected by treatment retention. Methods ...

Objective To investigate the risk of incident cognitive disorders in patients with primary Sjögren’s disease (pSjD) using nationwide Korean National Health Insurance Service data. Methods This ...

Background Adult-onset Still’s disease (AOSD) is a systemic autoinflammatory disorder lacking a gold-standard diagnostic criterion. Objective To develop and validate a clinically applicable model for ...