BACKGROUND: It remains unclear whether social determinants contribute to major ECG abnormalities (MEA), an early marker of cardiovascular disease, which predicts adverse cardiovascular events and ...
BACKGROUND: We aimed to examine how coronary artery calcium (CAC) and its progression relate to cognitive function in midlife, an important time for cognitive aging. METHODS: We studied participants ...
Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...
There is an emerging convergence between atherosclerotic cardiovascular disease and cancer, driven by shared risk factors and overlapping pathophysiologic mechanisms. Traditional factors, such as ...
BACKGROUND: Hypertensive disorders of pregnancy (HDP) are associated with increased long-term risk of both maternal and offspring cardiovascular disease. The incidence of HDP has increased ...
BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...
Clonal hematopoiesis (CH), the benign clonal expansion of hematopoietic stem cells, is often caused by somatic sequence variations in genes associated with hematologic malignancies. Over the past ...
BACKGROUND: Mental stress-induced myocardial ischemia is often clinically silent and associated with increased cardiovascular risk, particularly in women. Conventional ECG-based detection is limited, ...
Cardiac troponin (cTn) testing is an essential component of the diagnostic workup and management of acute coronary syndromes (ACS). Although over the past 15 years the diagnostic performance of the ...
In the largest study to date, we retrospectively included 213 patients evaluated from May 2020 to October 2022 in our CS Clinic diagnosed with presumed CS (169 with isolated CS; 44 with systemic ...
Background: Patients with intermediate-high risk pulmonary embolism (PE) have an elevated right-to-left-ventricular (RV/LV) diameter ratio and are at risk of early clinical decompensation and ...
In ischemic stroke, intravenous tenecteplase is noninferior to alteplase in selected patients and has some practical advantages. Several stroke centers in New Zealand changed to routine off-label ...
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