If you get VERR_NEM_VM_CREATE_FAILED when starting a virtual machine in Oracle VirtualBox, reboot the host system and if that doesn't work, check out these solutions.

Assuming VirtualBox has a command-line interface, you can write a script that does everything you want on start-up (or user-login) using launchd just as you would using init.

Once the driver is installed, launch Command Prompt as an administrator and execute the following command. sc start vboxdrv Finally, close CMD and launch VM to check if the issue is resolved.