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Predictions, picks and odds for NFL Week 16 game

Prisco's Week 16 NFL picks: Seahawks top Rams on 'TNF,' Packers edge Bears, Jaguars upset Broncos

This will be the second start for Philip Rivers for the Colts after he almost won at Seattle last week. The 49ers are 10-4 and pushing for a playoff spot. They blew out Tennessee last week, but the defense wasn't great. It won't matter as the 49ers will limit Rivers and Brock Purdy will play well. The 49ers keep on winning.

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Packers at Bears: Predictions, picks and odds for NFL Week 16 game

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NFL power rankings: See where the Broncos rank after Week 15

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Packers Power Rankings: Green Bay tumbles after Micah Parsons injury

The Green Bay Packers lost to the Denver Broncos this weekend, but more importantly, the team lost pass-rusher Micah Parsons for the rest of the season with a torn ACL.

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Packers Take Huge Slide in NFL Power Rankings After Broncos Loss

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Consensus NFL Power Rankings: Where Are Packers After Losing Game, Parsons?

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NFL Power Rankings: Week 16 Edition

The Rams keep rolling. They can cement their status as the NFL’s top team by sweeping the season series with Seattle on Thursday night.

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NFL Power Rankings, Week 16: Broncos, Jaguars climb; Packers head in wrong direction

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NFL Power Rankings for Week 16: Unpacking every game in two sentences

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NFL Week 16 picks: Expert looks at teams coming off shutout losses under proven betting system

This system looks at teams that didn't score the previous week and were playing a non-divisional team in Week 11 or later. In this spot, teams have covered the spread 31 times in 47 tries, winning by an average of 1.

RotoBaller on MSN

NFL Survivor Pool Picks: Week 16 Targets and Avoids

The top NFL survivor pool picks for Week 16 of the 2025 NFL season. Kevin's weekly survivor league pool targets and avoids -- expert picks for survivor leagues.

Bucs Wire

NFL Week 16 predictions, picks, win probabilities for games this week

NFL Week 16 picks, predictions, win probabilities for Buccaneers-Panthers, Jets-Saints, Vikings-Giants, Falcons-Cardinals, Steelers-Lions, more games.

Top 5 NFL Bets To Make Right Now | Week 16

NFL Week 16 is here and we’ve got the best NFL bets you need to know! Chris “Bear” Fallica, Geoff Schwartz, and Sammy Panayotovich break down their Top 5 NFL bets to place right now. If you’re looking for NFL Week 16 best bets,

NFL Week 16 staff picks: Seahawks-Rams showdown for NFC supremacy

It's "Butterfly Effect" season in the NFL, and nearly every game has downstream effects on someone's playoff hopes.

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Bengals at Dolphins: Predictions, picks and odds for NFL Week 16 game

USA Today's NFL experts make their picks for a Week 16 showdown between the Miami Dolphins and Cincinnati Bengals

SportsLine

NFL odds, lines, spreads: 2025 Week 16 picks, predictions from proven model: 5-way parlay pays nearly 25-1

The NFL playoff picture will begin to take shape as the NFL schedule enters Week 16. The NFC North Division title may be on the line on Saturday

NFL Week 16 confidence picks: Lock in the Texans against the Raiders

All odds referenced are courtesy of BetMGM as of publish time.

NFL Week 16 early predictions, odds: Best bets, picks to target before lines move

Prior to updates showing Week 15’s games, the Vikings are No. 22 in DVOA and will likely move into the teens after the win, while the Giants are No. 26 and dropping. If this line moves to 3.5, you’ll have the chance to arbitrage and middle it, with the chance both win if the Vikings win by a field goal.

SportsGrid on MSN

NFL Week 15 Top 5 Most Bet Anytime TDs: Lamar Jackson, Amon-Ra St. Brown Popular Picks

NFL Week 15 most bet anytime touchdown scorers at BetMGM, highlighting usage trends, matchup data, and scoring profiles driving public betting action.