Older adults are vulnerable to firearm-related harms. Medicare’s annual wellness visit presents an opportunity to engage older adults and their families or caregivers in conversations about firearms.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 2).

A 19-year-old woman presented with fever and cervical lymphadenopathy. The white-cell count was 2900 per microliter (reference range, 4000 to 11,000), and the lactate dehydrogenase level was ...

The World Health Organization recently issued its first global guidelines on the prevention, diagnosis, and treatment of infertility, but they pertain only to heterosexual couples.

Settlements of lawsuits against opioid manufacturers and other entities will shape drug policy for decades. Attention is needed to ensure that the funds will be dedicated to evidence-based activities.

Explore this issue of The New England Journal of Medicine (Vol. 380 No. 20).

When public health measures conflict with cultural, relational, and emotional practices surrounding severe illness and death, they may lead to uprisings that increase the risk of infection spread.

A 74-year-old man presented with a painful laceration on his leg that he had sustained 3 days earlier in waters off the Gulf Coast of Florida. Ecchymosis, swelling, and crepitus were observed in th ...

In this phase 3b, open-label, controlled trial, adult participants with obesity but without type 2 diabetes were randomly assigned in a 1:1 ratio to receive the maximum tolerated dose of tirzepatide ...

For decades, pancreatic ductal adenocarcinoma (PDAC) has been perhaps the clearest example of a cancer that is driven by a dominant oncogenic event yet is resistant to therapeutic exploitation. More ...

An 18-year-old man presented to the emergency department with generalized tonic–clonic seizures. MRI of the head showed numerous well-defined cystic lesions in the brain that were consistent with ...

Using data from digitized weekly surveillance reports of notifiable diseases for U.S. cities and states for 1888 through 2011, the authors derived a quantitative history of disease reduction in the ...