James Cook rushed for 216 yards and two touchdowns and the Bills defense had seven sacks in a 40-3 win over the Panthers.

The Bills face a big test Sunday when they host the Chiefs in their annual showdown. Here's an early look ahead to the game.

Maybe not at all, but it was an ominous sign of ... Eric Wood is the analyst, and Sal Capaccio is the sideline reporter. The network includes: 5 things that stood out in Bills' horrendous Week 6 loss ...

Takeaways from Columbus Blue Jackets' OT win in Buffalo include Wood's heroics, a Chinakhov update, offensive frustrations ...

Rachel Bush takes PEOPLE behind the scenes of the Buffalo Bills annual Halloween party. The NFL wife invited her husband ...

The Bills are getting a new $2.1 billion stadium in Orchard Park. Here's when it opens, where it's being built and whether it has a roof.

There is no love lost between the Buffalo Bills fans and the team’s heated rival, the Kansas City Chiefs. The latest example ...

Arizona Cardinals four time All-Pro safety, Budda Baker, has been named a trade target for the Buffalo Bills at the NFL ...

Snow, wind, and freezing cold have always defined Buffalo football. The Bills’ new stadium will keep that identity intact without building a dome. The $2.1 billion project is rising in Orchard Park ...

Plain and simple: Buffalo exhibits all the warning signs of a troubled team on defense. And no one play typified its struggles more than Falcons running back Bijan Robinson taking a handoff, making a ...

ORCHARD PARK - Losing to the New England Patriots is something the Buffalo Bills are quite familiar with. After all, they spent almost the entire first two decades of the 21st century turning that ...

Atlanta — The Buffalo Bills take on the Atlanta Falcons at 7:15 p.m., Monday at Mercedes-Benz Stadium in Atlanta. The game will air on ESPN. “SHOUT!” A Buffalo Bills football podcast is available on ...