Antivirulence drugs are a new type of therapeutic drug that target virulence factors, potentially revitalising the drug-development pipeline with new targets. As antivirulence drugs disarm the ...

Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for organisms ranging from single-celled bacteria to human beings. Some ...

Figure 1: The type III secretion system of Gram-negative bacterial pathogens injects virulence factors into host cells. The second class of TTSS-associated chaperones, which are the subject of this ...

Please provide your email address to receive an email when new articles are posted on . Infection is a challenging and dreaded complication of any surgical procedure, particularly so in orthopedic ...

The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new review by a Hackensack Meridian Center for Discovery and Innovation (CDI) scientist and ...

Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year. Caused by the bacterium Vibrio cholerae, ...

Heterogeneity is ubiquitous in real-world host populations, yet most theories assume homogeneity. Using a metapopulation model, we examine how host heterogeneities, such as uneven movement patterns ...

The visualization revealed that virulence activation is achieved through the interaction of ToxR or TcpP with the ...

The emergence of new variants of concern (VOC) has slowed down progress against the COVID-19 pandemic in 3 ways: 1. by increasing the transmissibility of the virus and hence the reproduction number; 2 ...