Injuries and veteran leadership clash as key defenders aim to dominate this crucial NFC West showdown. Keep your eyes on ...

Sunday's showdown in the desert will feature two teams that are coming off tough losses.

Key 49ers and Cardinals offensive stars face critical tests as both teams battle to regain momentum and establish dominance.

The San Francisco 49ers face their division rivals, the Arizona Cardinals, at State Farm Stadium in Glendale, Arizona on ...

Broadcast and streaming information for the San Francisco 49ers Week 11 matchup against the Arizona Cardinals at State Farm ...

With a burst of confetti and an official jersey swap, the University of the Pacific is now the official higher education ...

The prospects for the San Francisco 49ers' season remain strong, with a playoff berth and a deep January run in play. However ...

The San Francisco 49ers have officially made the call to start Brock Purdy against the Arizona Cardinals in Week 11. Purdy returns after six weeks on the sidelines following a turf toe injury he ...

How to watch the NBA game between the Indiana Pacers and the Toronto Raptors, as well as tip-off time and team news.

The Los Angeles Rams look to own the spotlight on Sunday as they battle the Seattle Seahawks for the lead in the NFC West at ...

The 8th-ranked Oregon Ducks are back in the national spotlight on Friday night as their pursuit of the College Football ...

Purdy returns as the starter Sunday when the 49ers (6-4) visit the Arizona Cardinals (3-6) at State Farm Stadium (Fox, 1:05 p ...