Nancy Guthrie, 84, was last seen at her Tucson home on Jan. 31 and was reported missing the following day. Authorities say her blood was found on the front porch.

Pima County Sheriff Chris Nanos told CBS News the suspect's backpack is one of the most promising leads in the case, as the search continues for Nancy Guthrie.

The Arizona sheriff leading the search for missing Nancy Guthrie has dismissed claims that the elderly matriarch’s disappearance was the result of a burglary gone bad. “This is somebody who disappeared from the face of the earth,

The search for missing 84-year-old Nancy Guthrie, mother of “Today” show host Savannah Guthrie, has stretched into a third, anguished week, with mounting pressure on investigators and a family grappling with uncertainty.

Authorities think Nancy Guthrie was abducted in the middle of the night from her Catalina Foothills home in the Tucson area.

The desperate search for Nancy Guthrie is entering its second week — as the 84-year-old mother of “Today” anchor Savannah Guthrie was last seen at her Arizona home on Jan. 31.

There was a large law enforcement presence near First and Orange Grove late Friday night in connection with the Nancy Guthrie disappearance.

As hundreds of federal and local agents scoured the Arizona desert and chased down potential leads in the nearly two weeks since Nancy Guthrie disappeared from her affluent neighborhood, families of other missing people are reminded how elusive answers can be.