The clinical effects of botulinum toxin have been recognised since the end of the 19th century. It is the most potent neurotoxin known and it is produced by the gram negative anaerobic bacterium ...

Objective: To assess the risk of recurrence of cerebral venous and sinus thrombosis (CVST) during subsequent pregnancy and puerperium in women with previous cerebral venous occlusive disease. Methods: ...

Hereditary neuropathy with liability to pressure palsy (HNPP) is characterised by recurrent mononeuropathies following minor trauma. We describe a case of fulminant HNPP beginning on the first day of ...

Objectives Guillain-Barré syndrome (GBS) is an acute clinical syndrome that is classically featured by rapidly evolving motor weakness, mild sensory loss and hypo- or areflexia. Uncommon variants such ...

Objective: To compare the HMPAO SPECT cerebral perfusion patterns in early and late onset Alzheimer’s disease. Methods: Twenty patients with early onset disease (<65 years) and 44 patients with late ...

Background: The high coincidence of organic vestibular and somatoform vertigo syndromes has appeared to support pathogenic models showing a strong linkage between them. It was hypothesised that a ...

Wallerian degeneration (WD) after ischaemic stroke is a well known phenomenon following a stereotypical time course. Whereas conventional magnetic resonance imaging fails to detect signal intensity ...

OBJECTIVE Necropsy confirmed clinical diagnostic accuracy for Alzheimer’s disease is claimed to exceed 90%. This figure contains two fallacies; it includes cases in which Alzheimer’s disease exists ...

OBJECTIVES Psychopathology has been reported to be prevalent both before and after surgical treatment for medically intractable temporal lobe epilepsy. Individual patients were evaluated prospectively ...

OBJECTIVES To establish the link between frontal lobe dysfunction and violent and criminal behaviour, based on a review of relevant literature. METHODS Articles relating evidence of frontal lobe ...

Influential models based on an increasing body of neuroimaging evidence propose that insular cortex integrates cognitive, affective, sensory and autonomic information to create a consciously perceived ...

Parkinson’s disease seems to occur more commonly in men than women based primarily on studies of death rates and prevalence. In recent years, several population based incidence studies of Parkinson’s ...