It’s been 16 days since Nancy Guthrie was reported missing, and investigators working the case that has captivated the nation’s attention are encountering a unique mix of challenges.

Nancy Guthrie, the 84-year-old mother of "TODAY" co-anchor Savannah Guthrie was last seen Jan. 31 when she was dropped off at her home in the Tucson, Arizona.

The Pima County Sheriff's Department blocked a residential street near Nancy Guthrie's home to conduct an investigation related to the case.

The discovery was revealed days after investigators had released surveillance videos of the masked person outside Nancy ...

Savannah Guthrie issued a new plea on Feb. 15 for the safe return of her 84-year-old mother, Nancy, as the suspected ...

The FBI has matched DNA from a glove found two miles from the home of NBC host Savannah Guthrie’s mother to a masked individual suspected of kidnapping the 84-year-old more than two weeks ago.

The Arizona sheriff leading the search for missing Nancy Guthrie has dismissed claims that the elderly matriarch’s disappearance was the result of a burglary gone bad. “This is somebody who ...

More than two weeks have passed since Nancy Guthrie disappeared.

The FBI says it recovered a DNA sample from the glove, which was found in a field a few miles from Guthrie's home.

The FBI says a glove found near Nancy Guthrie's home appears to match the one worn by a suspect seen in her home's doorbell camera footage. The DNA is currently being analyzed.

Savannah Guthrie still has "hope" two weeks after mom Nancy Guthrie was "taken" and pleaded with a possible kidnapper "to do ...