Prince Frederik of Luxembourg, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, has died after a lifelong battle with a rare genetic disorder known as POLG mitochondrial disease.

P rince Frederik of Luxembourg, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, died in Paris at age 22 on March 1—a day after Rare Disease Day—of a rare genetic disease known as POLG.

The beloved royal died on March 1 from POLG Mitochondrial disease — a rare genetic disorder that affects approximately one in 5,000 people.

Mei Fa Tan spoke exclusively to Us Weekly about what it was like to work with Luxembourg’s Prince Frederik before his death

Prince Frederik, the son of Europe's Prince Robert of Luxembourg, has died from a rare genetic disease, his family announced.

Prince Frederik of Luxembourg, who died at 22, spoke about the rare genetic disorder he navigated in a video released by The PolG Foundation he founded.

Prince Frederik of Luxembourg has died at the age of 22 from a rare genetic condition, according to a statement from his father, Prince Robert of Luxembourg, through the family's foundation. "It is with a very heavy heart that my wife and I would like to inform you of the passing of our son, The ...

Frederik de Nassau died on March 1, in Paris, a day after internationally recognized Rare Disease Day, which takes place on the last day of February.

Prince Frederik of Luxembourg died at 22 after years of struggling with the rare mitochondrial disease PolG, according to a statement issued by his parents, Prince Robert and Princess Julie, on Monday.