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Ohio State vs Penn State prediction, odds, line, time

Penn State Nittany Lions at Ohio State Buckeyes odds, picks and predictions

The Penn State Nittany Lions (3-4, 0-4 Big Ten) and the No. 1 Ohio State Buckeyes (7-0, 4-0) meet Saturday at Ohio Stadium in Columbus, Ohio.

· 10h · on MSN

Ohio State vs. Penn State score prediction by expert football model

· 15h · on MSN

Ohio State vs. Penn State prediction, odds, line, time: 2025 college football Week 10 picks by model

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Ohio State vs. Penn State football betting line, odds, spread | Week 10 2025

The No. 1 Ohio State Buckeyes (7-0) will face off against their Big Ten-rival, the Penn State Nittany Lions (3-4) in a matchup on Saturday, November 1, 2025 at Ohio Stadium.

· 16h

What to know about Ohio State’s game against Penn State

· 16h

Life in Simulation: Ohio State vs. Penn State

· 18h

Ohio State vs. Penn State: 2025 game preview and prediction

Julian Sayin enters this week’s game coming off the best performance of his career, throwing for a career-high 393 yards and tying his career-high with four touchdown passes in the win over Wisconsin...

· 21h

Ohio State football depth chart projection for Penn State game

· 21h

Staff picks for Penn State vs. Ohio State in Week 10

13hon MSN

LeBron James delivers surprise gift for Ohio State football before Penn State game

"LeBron James hooked up the Ohio State Buckeyes with special cleats inspired by his “Grand Opening” Nike LeBron 23," the account "Nice Kicks" posted. Although coach Ryan Day has yet to react to James' gift, he did tease James during "The Tonight Show" in January about how he would have been recruited.

Penn State football podcast on upset shot vs Ohio State, our favorite head coach candidate

Check out this week's Penn State football podcast with York Daily Record's Frank Bodani, PSU writer Mike Gross and former TV anchor Andrew Kalista.

19h

What we’re hearing on Penn State, Clark Lea, Lane Kiffin and more entering CFB’s Week 10

While Lane Kiffin appears to be the No. 1 target in the SEC, the Penn State opening appears to be more of a mystery now.