About 54,700 results
Open links in new tab
  1. Prostacyclin - Wikipedia

    Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.

  2. Prostacyclin Therapy for Pulmonary Arterial Hypertension

    Prostacyclin, a prostanoid metabolized from endogenous arachidonic acid through the cyclooxygenase (COX) pathway, is a potent vasodilator that has been identified as one of the …

  3. Prostacyclin - an overview | ScienceDirect Topics

    Prostacyclin refers to a member of the endogenous prostanoid family that is produced from arachidonic acid. It is released by pulmonary artery endothelial cells in the pulmonary …

  4. Prostacyclin: Functions, Health Impacts, and Medical Uses

    Jul 25, 2025 · Prostacyclin, also known as prostaglandin I2 (PGI2), is a naturally occurring lipid molecule within the human body. This potent substance serves as a regulator within the …

  5. Role of Prostacyclin (PGI2) Drug Class in Lung Function

    PAH may be characterized by abnormally low levels of prostacyclin, or PGI2, a naturally occurring metabolite of arachidonic acid that is endogenous to the body. Prostacyclin carries out several …

  6. Prostacyclin: an inflammatory paradox - Frontiers

    May 13, 2011 · Prostacyclin (PGI 2) is a member of the prostaglandin family of bioactive lipids. Its best-characterized role is in the cardiovascular system, where it is released by vascular …

  7. Physiology, Prostaglandin I2 - StatPearls - NCBI Bookshelf

    Aug 28, 2023 · Prostaglandin I2 (PGI), or prostacyclin, is one of the prostanoids, a group of local hormones that are best known for their roles in mediating inflammation. However, they also …

  8. Prostacyclin | chemical compound | Britannica

    The process of clot formation begins with an aggregation of blood platelets. This process is strongly stimulated by thromboxanes and inhibited by prostacyclin. Prostacyclin is synthesized …

  9. CV Pharmacology | Prostacyclin Receptor Agonists

    Prostacyclin (PGI 2) is a product of arachidonic acid metabolism within vascular endothelium and is a potent vasodilator.

  10. Prostacyclin - Wikiwand

    Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.