
Prostacyclin - Wikipedia
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.
Prostacyclin Therapy for Pulmonary Arterial Hypertension
Prostacyclin, a prostanoid metabolized from endogenous arachidonic acid through the cyclooxygenase (COX) pathway, is a potent vasodilator that has been identified as one of the …
Prostacyclin - an overview | ScienceDirect Topics
Prostacyclin refers to a member of the endogenous prostanoid family that is produced from arachidonic acid. It is released by pulmonary artery endothelial cells in the pulmonary …
Prostacyclin: Functions, Health Impacts, and Medical Uses
Jul 25, 2025 · Prostacyclin, also known as prostaglandin I2 (PGI2), is a naturally occurring lipid molecule within the human body. This potent substance serves as a regulator within the …
Role of Prostacyclin (PGI2) Drug Class in Lung Function
PAH may be characterized by abnormally low levels of prostacyclin, or PGI2, a naturally occurring metabolite of arachidonic acid that is endogenous to the body. Prostacyclin carries out several …
Prostacyclin: an inflammatory paradox - Frontiers
May 13, 2011 · Prostacyclin (PGI 2) is a member of the prostaglandin family of bioactive lipids. Its best-characterized role is in the cardiovascular system, where it is released by vascular …
Physiology, Prostaglandin I2 - StatPearls - NCBI Bookshelf
Aug 28, 2023 · Prostaglandin I2 (PGI), or prostacyclin, is one of the prostanoids, a group of local hormones that are best known for their roles in mediating inflammation. However, they also …
Prostacyclin | chemical compound | Britannica
The process of clot formation begins with an aggregation of blood platelets. This process is strongly stimulated by thromboxanes and inhibited by prostacyclin. Prostacyclin is synthesized …
CV Pharmacology | Prostacyclin Receptor Agonists
Prostacyclin (PGI 2) is a product of arachidonic acid metabolism within vascular endothelium and is a potent vasodilator.
Prostacyclin - Wikiwand
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.