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Differentiating CVID from Sarcoidosis I discuss protein gaps, antibody responses, and why CVID can sometimes look like sarcoidosis. Includes an on-screen correction about total IgG versus IgG4, also note that a single cutoff doesn't establish CVID and you would need more evidence to land a formal diagnosis More clinical pearls: youtube.com/conanliumd #medicine #meded #clinicalpearls #immunology #medicaleducation
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POV: Así funciona la opsonización 😂🦠 El plasmocito: “Ten, agarra esto…” 🔪 La bacteria: “¿Y esto?” El macrófago: 🚨 ¡CON QUE PORTANDO IgG, EH! Los plasmocitos producen IgG, que puede unirse a antígenos de la superficie bacteriana y actuar como opsonina. Los macrófagos reconocen la región Fc de estas IgG mediante receptores Fcγ, favoreciendo la fagocitosis. En pocas palabras: la IgG le pone la etiqueta de “cómete a este” a la bacteria. 😂 📚 Bibliografía: • Abbas AK, Lichtman AH, Pillai S. Cell
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