Chronic loneliness creates a long lasting stress state in the body. The brain interprets ongoing social isolation as a form of threat because humans rely on connection for safety and support. This perception activates stress pathways that influence cortisol, the main hormone responsible for regulating daily energy cycles. Cortisol normally rises in the morning to help the body wake up and gradually falls toward evening to prepare for rest. When loneliness persists, this natural rhythm becomes di
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